Caffeine, hydrochloride

CAS 5892-18-2 | ≥ 97 % HPLC

Product Details

Specifications

  • CAS Number: 5892-18-2
  • Purity: ≥ 97 % HPLC
  • Grade: Food grade
  • Molecular Formula: C8H11ClN4O2
  • Molecular Weight: 230.65 g/mol
  • Apperance: A white to off-white crystalline powder.
  • Application: Used as a central nervous system stimulant in pharmaceutical formulations.

Documentation

Production Manufacturer

Palkem India, based in Mumbai, India, is a prominent chemical company recognized for its reliable supply of high-quality chemicals across diverse industries. With a strong focus on customer satisfaction and continuous improvement, Palkem India has earned a reputation as a preferred supplier within the chemical sector. Offering an extensive product range, dependable delivery, and responsive customer service, Palkem India is well-positioned for ongoing growth and success.

Physicochemical properties

Physical Parameters

Parameters Value
Melting Point (MP) ~178–180 °C (decomposes)
Boiling Point (BP) -
Density -
Specific Gravity -
Solubility (Water) Highly soluble
Solubility (Ethanol) Soluble
Refractive Index -
Vapor Pressure -
Viscosity -
Phase (Room Temp.) Solid
Thermal Conductivity -
Heat Capacity -

Chemical Parameters

Parameters Value
pH (in solution) ~5.5 – 6.5
Chemical Stability Stable under ordinary conditions; protect from moisture
Flash Point -
Autoignition Temperature -
Oxidation State C: 0, +4; N: –3; O: –2; Cl: –1
Electronegativity -
Ionization Energy -
Chemical Reactivity Reacts with strong bases, decomposes at high temperatures
Functional Groups Purine alkaloid (xanthine derivative), hydrochloride salt
Spectroscopic Data (IR, NMR, UV-Vis)
UV-Vis λmax ~273 nm (caffeine chromophore)
IR (KBr) Strong C=O stretches ~1700 & 1655 cm⁻¹; C–N, C–C stretches 1550–1200 cm⁻¹
¹H-NMR (D₂O, 400 MHz) δ 3.27 (s, 3H, N1-CH₃), 3.50 (s, 3H, N3-CH₃), 4.05 (s, 3H, N7-CH₃), 7.88 (s, 1H, H-8)
¹³C-NMR (D₂O, 100 MHz) δ 27.8 (N1-CH₃), 29.7 (N3-CH₃), 33.9 (N7-CH₃), 107.8 (C-5), 141.6 (C-8), 149.4 (C-4), 151.2 (C-2), 155.2 (C-6)

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