Tirzepatide

CAS 2023788-19-2 | ≥ 98.5 % HPLC

Product Details

Specifications

  • CAS Number: 2023788-19-2
  • Purity: ≥ 98.5 % HPLC
  • Grade: Pharmaceutical grade
  • Molecular Formula: C225H348N48O68
  • Molecular Weight: 4813.45 g/mol
  • Apperance: White powder
  • Tirzepatide sample photo
  • Pharmacology: Tirzepatide is a dual GIP/GLP-1 receptor agonist.
  • Clinical effects: Weight reduction, changes in muscle composition, and cardiovascular outcomes.

Documentation

Production Manufacturer

Palkem India, based in Mumbai, India, is a prominent chemical company recognized for its reliable supply of high-quality chemicals across diverse industries. With a strong focus on customer satisfaction and continuous improvement, Palkem India has earned a reputation as a preferred supplier within the chemical sector. Offering an extensive product range, dependable delivery, and responsive customer service, Palkem India is well-positioned for ongoing growth and success.

Physicochemical properties

Physical Parameters

Parameters Value
Melting Point (MP) 152°C~156°C
Boiling Point (BP) -
Viscosity (For the solution) ~10-20 cP
Solubility Soluble in water;
Water solubility is very low (≈<1 mg/mL).
Soluble in dimethyl sulfoxide (DMSO).
Phase Solid at room temperature

Chemical Parameters

Parameters Value
pH (For the solution) ~5.0 - 6.0
Functional Groups Tirzepatide contains many amide (peptide) bonds linking its amino acids. Its side chains include primary/secondary amines (e.g. Lysine residues, N-terminus), carboxylates (Aspartate, Glutamate, and the fatty diacid moiety), aromatic rings (phenyl of Phe, indole of Trp, phenol of Tyr), and hydroxyl groups (Ser, Thr).
Amino Acid Sequence Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-lle-{Aib}Leu-Asp-Lys-lle-Ala-GIn-{diacid-C20-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-GIn-Trp-Leu-lle-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Spectroscopic Data

Characterized by:
Mass Spectrometry (MS): Exact mass confirmed (~4813 Da for free base).
Amino Acid Analysis: Confirms composition.
Peptide Mapping: (HPLC-MS/MS) confirms sequence.
Circular Dichroism (CD): For secondary structure.
NMR: For structural characterization (R&D).

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